Journal article
Risk factors for uncommon histologic subtypes of breast cancer using centralized pathology review in the Breast Cancer Family Registry
ME Work, IL Andrulis, EM John, JL Hopper, Y Liao, FF Zhang, JA Knight, DW West, RL Milne, GG Giles, TA Longacre, F O'Malley, AM Mulligan, MC Southey, H Hibshoosh, MB Terry
Breast Cancer Research and Treatment | SPRINGER | Published : 2012
Abstract
Epidemiologic studies of histologic types of breast cancer including mucinous, medullary, and tubular carcinomas have primarily relied on International Classification of Diseases-Oncology (ICD-O) codes assigned by local pathologists to define histology. Using data from the Breast Cancer Family Registry (BCFR), we compared histologic agreement between centralized BCFR pathology review and ICD-O codes available from local tumor registries among 3,260 breast cancer cases. Agreement was low to moderate for less common histologies; for example, only 55 and 26 % of cases classified as mucinous and medullary, respectively, by centralized review were similarly classified using ICD-O coding. We then ..
View full abstractGrants
Awarded by National Cancer Institute
Funding Acknowledgements
This study was supported through the National Cancer Institute, National Institutes of Health under RFA-CA-06-503, Cancer Care Ontario (U01 CA69467), Cancer Prevention Institute of California (U01 CA694117), University of Melbourne (U01 CA69638) and through cooperative agreements with members of the Breast Cancer Family Registry (BCFR) and Principal Investigators. The Australian Breast Cancer Family Study was also supported by the National Health and Medical Research Council of Australia, the New South Wales Cancer Council and the Victorian Health Promotion Foundation. The recruitment of controls by the Northern California Cancer Center was supported in part by National Institutes of Health Grant U01CA 71966. The recruitment of controls in Ontario was supported by the Canadian Breast Cancer Research Initiative. This study was also supported by a Ruth L. Kirschstein National Research Service Award T32 Training Grant. The content of this manuscript does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centers in the BCFR, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government or the BCFR. We acknowledge the important contribution of Dr. A. S. Whittemore to the development of the three studies.